Although there are insufficient studies on objective measures, studies also indicated that the subjective effects of AMP administration are linked to between-person variations in personality traits. Overall, findings indicate that AMP has mixed-effects on spatial WM and other cognitive functions, but it lacks effects on verbal WM. However, few studies reported the impacts of personality traits on the objective (such as WM) effects of AMP. Studies also showed that personality traits are associated with the subjective effects of AMP. Twenty-two reported effects of AMP on cognitive functions. Thirty-seven independent studies on other aspects of cognitive performance were identified. Seven studies found effects of AMP on spatial WM, but only one study found the effect of AMP on verbal WM. Nineteen WM studies were included in the current review. Narrative reviews of the influence of personality traits on the subjective and objective effects of AMP were included. An electronic search was performed in the PUBMED and SCOPUS databases. Previous double-blind controlled studies assessing the main effects of AMP on WM and other cognitive performances in healthy volunteers were systematically reviewed. The investigation also aimed to review the impact of personality traits on the subjective and objective effects of AMP and possible links between personality traits and effects of AMP. This research aimed to systematically review the acute effects of amphetamine (AMP), a dopamine-releasing agent, on working memory (WM) and other cognitive performances.
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